Figure 4.

Standard hemoglobin dissociation curve (black line) for Sprague-Dawley rats (modified from Cartheuser ³⁸) where arterial hemoglobin saturation (SaO₂%) is plotted against partial pressure of oxygen in arterial blood (PaO₂). Brain tissue pO₂ data have been superimposed from one of our earlier studies (brain tissue pO₂ was measured simultaneously in the presumed penumbra (P) and corresponding contralateral cortex using implanted Oxyflo/Oxylite probes¹⁹) to emphasize the expected SaO₂ changes associated with 40% O₂ oxygen challenge (OC) and perfluorocarbon (PFC)+40% O₂ in the contralateral cortex and P.