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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Int J Immunopathol Pharmacol. 2013 Jan-Mar;26(1):37–48. doi: 10.1177/039463201302600104

Figure 3. The profile of mediators of bone remodeling through the disease course.

Figure 3

The culture supernates of LNC were prepared as described in the legend to Figure 2. The levels of the indicated mediators of bone remodeling in these culture supernatants were measured using a Multiplex assay, and the results were expressed as pg/mL. RANKL, receptor activator of nuclear factor kappa-B ligand; OPG, osteoprotegerin; GM-CSF, granulocyte-macrophage colony-stimulating factor; OPN, osteopontin; Mtb, heat-killed M. tuberculosis H37Ra. *, p<0.05, comparing the level at each phase of arthritic rats with that of naïve rats.