Table 3.

Unadjusted and multivariate adjusted logistic regression of SNPs with erectile dysfunction for P<10⁻⁶

A. Unadjusted Results
Chromosome	SNP	Position	A1	A2	MAF**	Missing count	Hardy-Weinberg equilibrium P	Location of SNP to the nearest gene	Nearest Gene	p-value*
3	rs9810233	106493580	G	A	0.270	1	0.725	flanking_5UTR	ALCAM	6.98E-07
3	rs1920201	106518787	G	T	0.245	5	0.653	flanking_5UTR	ALCAM	8.60E-07
2	rs836589	173201324	A	G	0.186	8	0.521	flanking_3UTR	PDK1	1.63E-06
3	rs1438552	106545285	G	A	0.247	2	0.603	flanking_5UTR	ALCAM	1.72E-06
6	rs6931865	144121547	A	G	0.336	1	0.901	intron	PHACTR2	3.57E-06
3	rs950146	36655103	C	A	0.491	5	0.698	flanking_3UTR	STAC	4.32E-06
3	rs9850224	142057977	A	G	0.010	1	1	flanking_5UTR	SLC25A36	4.80E-06
1	rs2990510	195287281	G	T	0.305	0	0.556	intron	F13B	5.89E-06
1	rs10754210	195278734	A	G	0.304	1	0.513	intron	F13B	5.89E-06
2	rs7566884	173189446	G	A	0.177	1	0.393	flanking_3UTR	PDK1	6.39E-06
1	rs4520444	195408611	T	G	0.296	5	0.842	intron	ZBTB41	7.77E-06
1	rs5998	195276421	G	A	0.454	0	0.696	coding	F13B	8.30E-06
1	rs7518773	195278259	G	A	0.453	2	0.615	intron	F13B	8.30E-06
1	rs1332668	195272359	T	C	0.455	1	0.655	flanking_3UTR	F13B	8.50E-06

B. Multivariate Results*
Chrom	SNP	Position	A1	A2	MAF#	missing	Hardy- Weinberg equilibrium P	Location of SNP to nearest gene	Nearest Gene	Model	OR	95% CI		p-value
3	rs9810233	106493580	G	A	0.270	1	0.725	flanking_5UTR	ALCAM	M1	2.32	1.67	3.22	5.93E-07
3	rs1920201	106518787	G	T	0.245	5	0.653	flanking_5UTR	ALCAM	M1	2.26	1.63	3.14	9.39E-07
6	rs6931865	144121547	A	G	0.336	1	0.901	intron	PHACTR2	M1	2.02	1.50	2.74	4.85E-06
3	rs950146	36655103	C	A	0.491	5	0.698	flanking_3UTR	STAC	M1	0.48	0.35	0.66	4.77E-06
2	rs836589	173201324	A	G	0.186	8	0.521	flanking_3UTR	PDK1	M1	2.27	1.58	3.25	8.29E-06
3	rs950146	36655103	C	A	0.491	5	0.698	flanking_3UTR	STAC	M2	0.46	0.33	0.64	6.52E-06
6	rs6931865	144121547	A	G	0.336	1	0.901	intron	PHACTR2	M2	2.48	1.73	3.54	6.89E-07

^*Fishers exact test.

^**Minor Allele Frequency A1 is the minor allele.

^*All models run with additive tests for significance in PLINK with covariates.

^**Adjusting for cohort, treatment, cohort*treatment. (M1)

^***Adjusting for cohort, treatment, cohort*treatment, diabetes duration, age, initial HgbA1c at eligibility. (M2)

^#Minor Allele Frequency