Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
SIRT1, tissue maintenance, and tumorigenesis. SIRT1 mediates the stress response in hematopoietic stem cells (HSCs) and promotes HSC survival and tissue homeostasis. This stress response pathway is hijacked by leukemic stem cells (LSCs) and promotes LSC survival and disease evolution.
