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. Author manuscript; available in PMC: 2013 Sep 6.
Published in final edited form as: Expert Rev Gastroenterol Hepatol. 2008 Jun;2(3):323–335. doi: 10.1586/17474124.2.3.323

Figure 3. Cortical evoked potentials after anal electrical stimulation.

Figure 3

Typical examples from (A) one patient with predominant IBS-C, (B) a healthy control and (C) a dyssynergic constipated patient. The anal cortical evoked potentials latencies are shorter and the amplitudes are higher in IBS-C than control or dyssynergia patient. By contrast, the anal cortical evoked potential latency for P1 is prolonged, and the N2 amplitude is lower in the subject with dyssynergia. These preliminary data suggest that the gut–brain axis is altered in subjects with functional anorectal disorders. IBS-C: Predominant constipation irritable bowel syndrome.