Table 1.
Effect of CRF on the firing of NI neurons and their RLN3 phenotype
| Response to CRF | Activated | Inhibited | Unaffected | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Response to medial septum stimulation | AD | OD | Sp | AD | OD | Sp | AD | OD | Sp |
| RLN3 +ve (n= 9) | 5 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| RLN3 –ve (n= 13) | 0 | 0 | 1 | 1 | 5 | 2 | 0 | 0 | 4 |
Values are the number of recorded NI neurons verified for the presence or absence of RLN3-immunoreactivity following juxtacellular labelling. Abbreviations: AD, antidromic; CRF, corticotrophin-releasing factor; NI, nucleus incertus; OD, orthodromic; Sp, neither AD nor OD, but spontaneously firing.