TABLE 1.
Summary of protein-protein interactions
This table summarizes all interacting partners that were further tested in this study. Additional proteins identified on domain array screen but not further tested are listed in supplemental Table I. Co-IP, co-immunoprecipitation.
| Symbol | Name | Array | Binds to PRRG4 in GST pulldown | Binds to PRRG4 in Co-IP | Binds to PRRG2 |
|---|---|---|---|---|---|
| MAGI-1 | Membrane-associated guanylate kinase-related | WW | YES | YES | YES |
| MAGI-3 | Membrane-associated guanylate kinase-related | WW | YES | Not testeda | Not tested |
| YAP | Yes-associated protein | WW | YES | YES | YESb |
| TAZ/WWTR1 | Transcriptional co-activator with PDZ binding motif | WW | YES | YES | YES |
| NEDD4L | E3 ubiquitin-protein ligase | WW | YES | Not testeda | YES |
| NEDD4 | E3 ubiquitin-protein ligase | WW | YES | Not testeda | YESc |
| Lyn | Src family of non-receptor protein tyrosine kinase Lyn | SH3 | NO | Not testeda | Not tested |
| OSTF | OSF: osteoclast-stimulating factor 1 | SH3 | NO | NO | Not tested |
| Grb2 | Growth factor receptor-bound protein 2 | SH3 | Not testedd | NO | Not tested |
| βpix/cool1/Y124 | PAK-interacting exchange factor β | SH3 | NO | NO | Not tested |