Table 2.
Performance on Constituent Tests of the Executive Function and Verbal Memory Composites by Treatment Groupa
| Test | Mean z Score (SE)
|
|
|---|---|---|
| GHRH Group | Placebo Group | |
| Executive function | ||
| Task Switching accuracy | 0.29 (0.13) | −0.13 (0.12) |
| Stroop Color-Word Interference RT | 0.27 (0.13) | −0.14 (0.13) |
| SOPT accuracy | 0.32 (0.13) | 0.06 (0.12) |
| Word Fluency | 0.16 (0.13) | 0.15 (0.13) |
| Verbal memory | ||
| Total Story Recall | 0.32 (0.13) | 0.10 (0.12) |
| HVLT total recall | 0.28 (0.14) | 0.16 (0.13) |
Abbreviations: GHRH, growth hormone–releasing hormone; HVLT, Hopkins Verbal Learning Test; RT, reaction time measured using voice onset latency; SOPT, Self-Ordered Pointing Test.
a
Values represent mean change in performance due to treatment (averaged across weeks 10 and 20) relative to baseline, adjusted for age, baseline MMSE score, and educational level.