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Hydrophilic (light blue) and hydrophobic (orange) isocontour surfaces of FAAH-1 (A) and COX-2 (B). For the sake of clarity, relevant residues are highlighted as stick models with C atoms colored in cyan. The protein is shown as transparent cyan tube. Substrates are methyl arachidonyl fluorophosphonate in FAAH and arachidonic acid in COX-2.
