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. 2013 Sep 3;4:2041731413503357. doi: 10.1177/2041731413503357

Table 1.

Different types of drug delivery system.

Drug delivery system Structure Chemical properties References
Liposomes graphic file with name 10.1177_2041731413503357-img1.jpg Consists of hydrophobic tail and hydrophilic head group 27–29
Forms closed vesicles with an aqueous core
Internal aqueous domain between the lipid bilayers
Encapsulation of drugs occurs either in the aqueous space or intercalated into the bilayer
Dendrimers graphic file with name 10.1177_2041731413503357-img2.jpg Hyper branched and globular macromolecules 30–32
Well defined core, backbone and multivalent periphery
By hydrophobic and electrostatic interactions, incorporate biomolecules
Convergent – endo-receptor
Divergent – exo-receptor
Carbon nanotubes graphic file with name 10.1177_2041731413503357-img3.jpg Rolling up a single layer of grapheme sheet – single walled 33–37
Rolling up many layers to form concentric cylinders – multi-walled
Gold nanoparticles graphic file with name 10.1177_2041731413503357-img4.jpg Gold nanoparticle serves as core 8,38
Photosensitive
Iron oxide nanoparticles graphic file with name 10.1177_2041731413503357-img5.jpg Superparamagnetic particles 8,39
Need trigger to release biomolecules, for example, laser irradiation
Titanium dioxide nanoparticles graphic file with name 10.1177_2041731413503357-img6.jpg Self-ordered 40–42
Nano-tubular structure
Photodynamic therapy
Silica nanoparticles graphic file with name 10.1177_2041731413503357-img7.jpg Mesoporous structure 7, 23, 25
Honeycomb-like structure
Active surface