Penile elastin content is decreased in Eln+/− vs. Wt mice. (A) Elastin content, as measured by desmosine quantification, was significantly lower in penile tissue from Eln+/− vs. Wt mice (N = 8–10/group, *P < 0.05, t-test). (B) Tropoelastin mRNA, as a fraction of total 18s rRNA, was significantly decreased in penile tissue from Eln+/− vs. Wt mice. The fold change of tropoelastin mRNA expression, referred to the Wt mice, is presented (N = 9/group, *P < 0.05, t-test).