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. Author manuscript; available in PMC: 2013 Sep 6.
Published in final edited form as: Pestic Biochem Physiol. 2009 Sep 10;97(2):87–92. doi: 10.1016/j.pestbp.2009.09.001

Figure 2.

Figure 2

Pyrazoline RH-3421 shifts the steady state slow inactivation curve in the direction of hyperpolarization. Ionic current traces were scaled by a common factor so that the peak at −120 mV matched the peak before treatment. Peak INa was depressed most at depolarized potentials, whereas outward current, Ik, was not affected by the treatment. The graph shows plots of peak current normalized to the value at −120 mV. RH-3421 (10 μM) appears to shift the steady-state inactivation relation to the left by 8.6 mV [5].