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. 2013 Jul 22;122(10):1793–1801. doi: 10.1182/blood-2013-06-508952

Figure 3.

Figure 3

C3 is rapidly inactivated after binding to transfused incompatible KEL RBCs. (A) Total C3 bound to circulating KEL2 RBCs in animals passively transferred with polyclonal anti-KEL (black bars, solid histograms) or saline (open bars, shaded histograms); representative plots are shown. (B) Active forms of C3 (C3/C3b/iC3b) bound to circulating KEL2 RBCs in animals passively transferred with polyclonal anti-KEL (black bars, solid histograms) or saline (open bars, shaded histograms). These data are representative of 3 independent experiments, with 3-5 animals/group/experiment. *P < .05.