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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: J Struct Biol. 2013 Apr 30;183(1):95–98. doi: 10.1016/j.jsb.2013.04.008

Figure 2. DNA origami gold nanoparticle helices as molecular handedness standards.

Figure 2

Left-handed DNA origami gold nanoparticle helices (one example in red box) were mixed together with colloidal gold and Escherichia coli lysates, plunge-frozen, and imaged tomographically. An isosurface representation of the DNA origami gold nanoparticle helix with the attached 9 gold particles (yellow) and the modeled helix (white) is shown in the insets on the left (produced with 3dmod). Rotating the helix around the “x” (horizontal) axis reveals that the correct handedness has been maintained throughout the process (particle 1 is in the foreground and 9 is in the background). Bar: 200 nm.