. 2013 Aug 10;10:256. doi: 10.1186/1743-422X-10-256

Table 2.

Evolutionary characteristics of HBV genotypes based on the HBcAg gene using the uncorrelated log normal relaxed clock model produced by BEAST

HBV genotype	Location, year reported	HBV TMRCA (years; 95% HPD)	Emergence time (year)
HBV genotype	Location, year reported	*Substitution rate (CR) 1.127 (0.925–1.329)**	Emergence time (year)
TMRCA(A)	Japan,1988 [20]	118 (54–194)	1894
TMRCA (B)	Japan,1988 [20]	184 (78–323)	1828
TMRCA (D)	Japan,1988 [20]	133 (65–230)	1879

*Substitution rate are expressed as 10^-3 substitutions per site per year.