Table 2.
Expression of regulatory core transcription factors in melanoma cell lines
| Cell line | NANOG | OCT4 | SOX2 |
|---|---|---|---|
|
MZ2 |
- |
- |
- |
|
D10 |
+ + |
+ |
- |
|
Me39 |
+ + |
+ + |
- |
|
WM115 |
+ |
+ |
+ |
|
RE |
+ + |
+ + |
- |
|
Me59 |
- |
+ |
- |
|
Me67 |
+ |
- |
- |
|
Na8 |
- |
- |
- |
| HBL | + | - | - |
NANOG = Nanog homeobox; OCT4 = POU-domain transcription factor; SOX2 = SRY (sex determining region Y)-box2; (-) = no expression (<10-3); (+) = moderate expression (≥10-3<10-2); (+ +) = strong expression (≥10-2). Expression level of TF gene reported as 2–Ct, where Ct = (Ct [TF gene] - Ct [ACTB]) sample.