Table 1. Performance of three LED-based fluorescence microscopy devices in detection of tuberculosis in HIV-positive suspects in Kampala, Uganda, per specimen analysis.
| ZN | Routine FM | iLED | Fraen | Lumin | |
| Sensitivity * | 31.1% (51/164) 24.1–38.8 | 32.9% (54/164) 25.8–40.7 | 40.2% (66/164) 32.7–48.2 | 42.1% (69/164) 34.4–50.0 | 38.4% (63/164) 30.9–46.3 |
| 3+ | 9 | 9 | 11 | 12 | |
| 2+ | 13 | 20 | 18 | 20 | |
| 1+ | 17 | 25 | 24 | 19 | |
| Scanty | 12 | 11 | 16 | 12 | |
| No grading | 0 | 1 | 0 | 0 | |
| Specificity * | 99.3% (425/428) 98.0–99.9 | 99.1% (424/428) 97.6–99.7 | 93.2% (399/428) 90.4–95.4 | 91.6% (392/428) 88.5–94.0 | 91.6% (392/428) 88.5–94.0 |
| PPV | 94.4% (51/54) 84.6–98.8 | 93.1% (54/58) 83.3–98.1 | 69.5% (66/95) 59.2–78.5 | 65.7% (69/105) 55.8–74.7 | 63.6% (63/99) 53.4–73.1 |
| NPV | 79.0% (425/538) 75.3–82.4 | 79.4% (424/534) 75.7–82.8 | 80.3% (399/428) 76.3–84.0 | 80.5% (392/487) 76.7–83.9 | 79.5% (392/493) 75.7–83.0 |
*
For sensitivity calculations, the denominator is the number of specimens for which the culture was positive for MTB. For specificity, the denominator shows the number of culture negative specimens.