Table 5. Sensitivities compared to positive culture (LJ or MGIT) at different CD4 T cell strata.
| FM mic oscope | Reader 4: iLED | Reader 4: Fraen | Reader 4: Lumin | Reader 5: iLED | Reader 5: Fraen | Reader 5: Lumin | Reader 6: iLED | Reader 6: Fraen | Reader 6: Lumin | Overall: iLED | Overall: Fraen | Overall: Lumin | Overall-4: iLED | Overall-4: Fraen | Overall-4: Lumin |
| CD4<100 | 23.0% (3/13) (5.0–53.8) | 30.8% (4/13) (9.0–61.4) | 30.8% (4/13) (9.1–61.4) | 20.0% (1/5) (0.5–71.6) | 20.0% (1/5) (0.5–71.6) | 20.0% (1/5) (0.5–71.6) | 30.0% (3/10) (6.7–65.2) | 60.0% (6/10) (26.2–87.8) | 30.0% (3/10) (6.7–65.2) | 25.0% (7/28) (10.7–44.9) | 39.2% (11/28) (21.5–59.4) | 28.6% (8/28) (13.2–48.7) | 26.7% (4/15) (7.8–55.1) | 46.7% (7/15) (21.2–73.4) | 26.7% (4/15) (7.8–55.1) |
| CD4 101–250 | 33.3% (4/12) (10–65) | 41.7% (5/12) (15.2–72.3) | 33.3% (4/12) (10–65) | - | - | - | 24.0% (6/25) (9.4–45.1) | 28.0% (7/25) (12.1–49.4) | 20.0% (5/25) (6.8–40.7) | 24.4% (10/41) (12.4–40.3) | 29.3% (12/41) (16.1–45.5) | 21.9% (9/41) (10.6–37.6) | 20.7% (6/29) (8.0–39.7) | 24.1% (7/29) (10.3–43.5) | 17.2 % (5/29) (5.8–35.8) |
| CD4>250 | 53.1% (25/47) (38.0–67.9) | 55.3% (26/47) (40.1–69.8) | 53.1% (25/47) (38.1–67.9) | 66.7% (8/12) (34.9–90.0) | 66.7% (8/12) (34.9–90.0) | 58.3% (7/12) (27.7–84.8) | 41.7% (10/24) (22.1–63.3) | 33.3% (8/24) (15.6–55.3) | 33.3% (8/24) (15.6–55.3) | 51.8% (43/83) (40.6–62.9) | 50.6% (42/83) (39.3–61.8) | 48.1% (40/83) (37.1–59.4) | 50.0% (18/36) (32.9–67.0) | 44.4% (16/36) (27.9–61.9) | 41.7% (15/36) (25.5–59.2) |
| Overall | 44.4% (32/72) (32.7–56.6) | 48.6% (35/72) (36.7–60.7) | 45.8% (33/72) (34.0–58.0) | 42.9% (9/21) (21.8–66.0) | 42.9% (9/21) (21.8–66.0) | 38.1 % (8/21) (18.1–61.6) | 32.2% (19/59) (20.6–45.6) | 35.6% (21/59) (23.6–49.1) | 27.1 % (16/59) (16.3–40.2) | 39.5% (60/152) (31.6–47.7) | 42.8% (65/152) (34.8–51.0) | 37.5% (57/152) (29.8–45.7) | 35.0% (28/80) (24.7–46.4) | 37.5% (30/80) (26.9–49.0) | 30.0% (24/80) (20.2–41.2) |
Empty cells under reader 5 show that there were 13 patients and all tested negative for all 3 tests (i.e. iLed, Lumin, and Fraen). Overall-4 represents the overall sensitivities of readers 5 & 6 excluding reader 4 who had the highest false positivity rate. Table includes only those patients with a CD4 count record.