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. 1972 Sep;24(3):328–333. doi: 10.1128/am.24.3.328-333.1972

Recovery of Dengue Viruses from Tissues of Experimentally Infected Rhesus Monkeys

Nyven J Marchette 1,2, Scott B Halstead 1,2, Donald R Nash 1,2,1, Andrew C Stenhouse 1,2,2
PMCID: PMC376519  PMID: 4627963

Abstract

A tissue explant culture technique for the recovery of dengue virus from experimentally infected monkey tissue is described and compared with tissue culture assay of tissue triturates and co-cultivation of trypsinized cells in cell cultures. The most efficient technique was one in which minced tissue was explanted in co-culture with dengue virus-susceptible LLC-MK2 monkey kidney cells. This technique shows promise of being useful for detection of virus in autopsy material from fatal dengue hemorrhagic fever cases.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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