Table 1. Characteristics of the 96 Active Pulmonary TB patients included in the study.
Active pulmonary TB patients | ||||
HIV-infected (N = 38) | HIV-uninfected (N = 58) | All (N = 96) | p value HIV-infected Vs HIV-uninfected | |
Age median (IQR) | 38.0 (33.75–40.25) | 37.0 (21.75–45.0) | 38.0 (30.5–42.0) | 0.4288 |
Male/female | 33/5 | 38/20 | 71/25 | 0.0311 |
Male prevalence (%; 95% CI)) | 86.8 (71.9–95.6) | 65.5 (51.9–77.5) | 74.0 (64.5–82.1) | |
Main Clinical symptoms | ||||
Cough (%) | 23/38 (60.5%) | 58/58 (100.0%) | 91/96 (94.8%) | <0.0001 |
Weight loss (%) | 33/38 (86.8%) | 50/58 (86.2%) | 83/96 (86.5%) | 1.0 |
Fever (%) | 24/38 (63.2%) | 33/58 (56.9%) | 57/96 (59.4%) | 0.6714 |
Smear microscopy positive (%) | 19/38 (50.0%) | 46/58 (79.3%) | 65/96 (67.7%) | 0.037 |
Smear microscopy grade | ||||
Negative (%) | 19 (50.0%) | 12 (20.7%) | 31 (32.3%) | 0.037 |
Positive: scanty (%) | 3 (7.9%) | 6 (10.3%) | 9 (9.4%) | 1.0 |
Positive:+(%) | 6 (15.8%) | 12 (20.7%) | 18 (18.8%) | 0.6034 |
Positive:++(%) | 8 (21.1%) | 17 (29.3%) | 25 (26.0%) | 0.4771 |
Positive:+++(%) | 2 (5.3%) | 11 (19.0%) | 13 (13.5%) | 0.0701 |
Culture positive (%) | 17/38 (44.7%) | 46/58 (79.3%) | 63/91 (69.2%) | 0.0018 |
TB confirmed (%) | 44.7% | 79.3% | 69.2% | |
Clinical TB in % (95% CI) | 55.3% (30.8–99.5) | 20.7% (11.2–33.4) | 30.8% | 0.0018 |
TST tested (%) | 33/38 (86.8%) | 20/58 (33.3%) | 53/96 (55.2%) | |
TST positive (%) | 17/33 (51.5%) | 17/20 (85.0%) | 34/53 (64.2%) | 0.0185 |
Median TST (IQR) | 10.0 (0–20) | 16.5 (10–22) | 15.0 (0–20.0) | 0.0240 |
Clinical TB suspicion (%) | ||||
Very high (%) | 19 (50.0%) | 51 (87.9%) | 70 (72.9%) | 0.0001 |
High (%) | 19 (50.0%) | 7 (12.1%) | 26 (27.1%) | 0.0001 |
Low (%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | NA |
Footnotes: TB: tuberculosis; HIV: human immunodeficiency virus; TST: tuberculin skin test with a cut-off point at 10 mm; NA: not available.