Table 3.
Effects of DES and omeprazole, administered intraduodenally, on the biochemical parameters of gastric juice obtained from pylorus-ligature in rats
| Animal group | treatment 5 ml/kg | Volume (ml) | pH | Acid output [H+] mEq/L |
|---|---|---|---|---|
| A |
Control group (5% Tween 80) |
3.5 ± 0.015 |
3.83 ± 0.088 |
95 ± 0.88 |
| B |
Omeprazole (30 mg/kg) |
2.71 ± 0.015* |
6.17 ± 0.015* |
83 ± 1.15* |
| C |
DES (5 mg/kg) |
3.1 ± 0.12* $ |
4.92 ± 0.012*$ |
92 ± 0.58*$ |
| D |
DES (10 mg/kg) |
2.87 ± 0.12* |
5.98 ± 0.01* |
89 ± 0.88*$ |
| E | DES (20 mg/kg) | 2.94 ± 0.008* | 5.96 ± 0.01*$ | 90 ± 0.33*$ |
Results are expressed as mean ± S.E.M. (n = 6 rats).* indicate p < 0.05 compared to control group. $ indicate p < 0.05 compared to omeprazole.