Table 3. Diagnosis of perioperative myocardial infarction (MI).
Universal definition of MI (Type 5 MI)16 | Definition of MI SYNTAX study 17 | Definition of MI used in present study |
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Increase of biomarkers greater than 5x99th percentile upper reference limit during first 72 h following CABG; Pathological Q-waves or new left bundle-branch block, or angiographically documented new graft or native coronary artery occlusion, or imaging evidence of new loss of viable myocardium | Withinthefirst7dayspostintervention (PCIorCABG): Either new, abnormal Q waves and 1 ratio of peak creatine kinase–MB (CK-MB)/peak total CK >10% or new, abnormal Q-waves and 1 plasma level of CK-MB 5× upper limit for normal; 7daysafteranyinterventionprocedure (PCIorCABG): either new, abnormal Q waves or enzyme changes defined as more than 10% of the ratio of peak CK-MB/peak total CK on one or more than one sample (if no ratio is available—one or more than 1 plasma level of CK-MB 5× upper limit for normal) | 2 or more of the 3 following criteria within the first 7 days following CABG:1. new Q-wave or new left bundle-branch block compared to the preoperative echocardiography (ECG); 2. creatine kinase-MB (CK-MB) >60 mg/l; 3. postoperative severe wall motion abnormalities in ECG corresponding with ischemic ECG changes or angiographically documented new graft or native coronary artery occlusion or myocardial necrosis diagnosed by autopsy |
PCI, percutaneous coronary intervention; CABG, coronary artery bypass grafting