Figure 2. Comparison of airway reactivity to methacholine (MCh) in saline- and ovalbumin-challenged mice (open circles and closed circles respectively).

a) In vivo responses, measuring change in airway resistance (saline, ovalbumin n = 12, 8 respectively), b) in vitro responses in trachea, measuring change in force (saline, ovalbumin n = 18, 21) and c) in vitro responses in lung slices, measuring % decrease in small airway lumen area (saline, ovalbumin n = 9, 7). Data is expressed as mean ± S.E.M. *p<0.05 compared with saline controls.