Table 1. Comparison of BAL fluid in wild-type and dominant negative (DN) MafB transgenic mice.
| Wild-type n=17 | DN MafB n=21 | |
|---|---|---|
| Weight (g) | 23.3 ± 3.5 | 22.1 ± 3.5 |
| BALF volume (mL) | 5.3 ± 0.3 | 5.3 ± 0.3 |
| Cell concentration (×104 /mL) | 2.0 ± 0.6 | 1.2 ± 0.5** |
| Cell fractionation (×102/mL) | ||
| Macrophage | 186.6 ± 59.3 | 107.0 ± 42.9** |
| Neutrophil | 1.4 ± 1.4 | 0.4 ± 0.7* |
| Lymphocyte | 1.9 ± 2.0 | 1.1 ± 0.3 |
| Eosinophil | 0.3 ± 1.0 | 0.0 ± 0.0 |
| Mononuclear cells | 6.6 ± 3.6 | 7.1 ± 4.7 |
| Cell fractionation (%) | ||
| Macrophage | 95.8 ± 2.3 | 91.4 ± 4.0* |
| Neutrophil | 0.1 ± 0.3 | 0.1 ± 0.3 |
| Lymphocyte | 2.2 ± 1.4 | 1.9 ± 1.2 |
| Eosinophil | 0.0 ± 0.0 | 0.0 ± 0.1 |
| Mononuclear cells | 1.8 ± 1.2 | 6.6 ± 3.2** |
* P < 0.01, **** P < 0.0001 versus wild-type mice