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LINE-1 methylation and plasma SAM by DNMT1 rs2114724 genotype in men (A) and women (B). * Adjusted for age at blood draw and serum creatinine level. ** Black line: the wild type genotype (CC) (n = 90 for men and n = 126 for women); red line: variant genotypes (CT and TT) (n = 93 for men and n = 118 for women); dashed lines: upper and lower 95% confidence intervals.
