Table 2.

Statistical summaries of biases of correlation coefficients

	Min.	1st Qu.	Median	3rdQu.	Max.
B(rxy)	0.022	0.078	0.099	0.132	0.308
$$B\left({\overline{r}}_{\mathit{\text{xy}}}\right)$$	0.021	0.062	0.072	0.083	0.153
$$B\left(r_{\mathit{\text{xy}}}^{\ast }\right)$$	0.019	0.049	0.057	0.067	0.141
$$B\left({\overline{r}}_{\mathit{\text{xy}}}^{\ast }\right)$$	0.018	0.049	0.057	0.065	0.132

B(r_xy) – bias of the Pearson correlation coefficients estimated directly from the large expression matrix;$\mathit{B}\mathbf{\left(}{\overline{\mathit{r}}}_{\mathit{\text{xy}}}\mathbf{\right)}$ – bias of the average of correlations between expression profiles within i = 1,19 groups; B(rxy ∗) – bias of the Pearson correlation coefficients estimated directly from the pooled residuals;$\mathit{B}\mathbf{\left(}{\overline{\mathit{r}}}_{\mathit{\text{xy}}}^{\mathbf{\ast }}\mathbf{\right)}$ – bias of the average of correlations between expression residuals within i = 1,19 groups.