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. 2013 Sep 6;8(9):e74928. doi: 10.1371/journal.pone.0074928

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© 2013 Li et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) The sensitivity of MCF-7 control and 53BP1 knockdown MCF-7 cells to 5-Fu after knockdown of TS and DPYD at the indicated time point. MCF-7 control cells, left; 53BP1 knockdown MCF-7 cells, right. (B) When the MCF-7 control and 53BP1 knockdown MCF-7 cells were treated for 48 h, the relative survival of each breast cell lines was tested with MTT assay.