Table 4.
Comparative analysis of the associations between PCT, hsCRP and incident mortality
| Subjects | Outcome |
PCT |
hsCRP |
||
|---|---|---|---|---|---|
| HR (95% CI)a | P | HR (95% CI)a | P | ||
| All subjects |
All-cause mortality |
1.15 (1.04 to 1.26) |
0.006** |
1.08 (0.98 to 1.19) |
0.100 |
| Cancer mortality |
1.23 (1.06 to 1.41) |
0.005** |
1.02 (0.89 to 1.16) |
0.788 |
|
| CVD mortality |
1.08 (0.89 to 1.30) |
0.425 |
1.24 (1.03 to 1.49) |
0.025* |
|
| Mortality from causes other than cancer and CVD |
1.15 (0.95 to 1.39) |
0.161 |
1.07 (0.89 to 1.28) |
0.483 |
|
| Men |
All-cause mortality |
1.13 (1.00 to 1.27) |
0.047* |
1.09 (0.97 to 1.23) |
0.156 |
| Cancer mortality |
1.29 (1.08 to 1.54) |
0.006** |
0.96 (0.80 to 1.14) |
0.632 |
|
| CVD mortality |
1.04 (0.83 to 1.30) |
0.741 |
1.30 (1.01 to 1.66) |
0.037* |
|
| Mortality from causes other than cancer and CVD |
1.07 (0.86 to 1.34) |
0.556 |
1.16 (0.92 to 1.47) |
0.220 |
|
| Women | All-cause mortality |
1.13 (0.97 to 1.32) |
0.106 |
1.07 (0.92 to 1.24) |
0.362 |
| Cancer mortality |
1.09 (0.88 to 1.35) |
0.430 |
1.13 (0.92 to 1.38) |
0.261 |
|
| CVD mortality |
1.19 (0.87 to 1.62) |
0.286 |
1.13 (0.84 to 1.51) |
0.433 |
|
| Mortality from causes other than cancer and CVD | 1.21 (0.87 to 1.67) | 0.251 | 0.92 (0.68 to 1.23) | 0.568 | |
Cox regression analysis adjusted for age, sex, hypertension, diabetes, LDL, HDL, TG, renal function, BMI and smoking. aThe HR values are expressed as mean HR per quartile of the respective biomarker. BMI, body mass index; CI, confidence interval; CVD, cardiovascular disease; HDL, high-density lipoprotein; HR, hazard ratio; hsCRP, high sensitivity C-reactive protein; LDL, low-density lipoprotein; PCT, procalcitonin; TG, triglycerides. *P <0.05, **P <0.01.