Table 1.
Estimated fold change of 10 genes from one sample of simulated dataset2 using NPEBSeq, DESeq and edgeR
| gene_ID |
9995 |
9996 |
9511 |
9032 |
9045 |
9030 |
9082 |
3 |
1 |
| Poisson mean under condition A |
0.7741 |
1.4868 |
11.5416 |
424.1334 |
5.2419 |
5.2419 |
112.1307 |
0.7741 |
86.6691 |
| Poisson mean under condition B |
3.0318 |
5.8233 |
45.2038 |
103.8228 |
1.2832 |
1.2832 |
27.4483 |
0.758 |
84.8622 |
| TRUE fold change |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
1 |
1 |
| observed #reads under condition A |
0 |
0 |
2 |
365 |
34 |
13 |
89 |
0 |
80 |
| observed #reads under condition B |
4 |
2 |
37 |
111 |
0 |
1 |
83 |
4 |
72 |
| estimated fc by NPEBSeq |
2.5813 |
1.8077 |
13.2633 |
3.3515 |
18.9702 |
5.8962 |
1.1168 |
2.5813 |
1.0156 |
| estimated fc by DESeq |
inf |
inf |
18.6932 |
3.2543 |
inf |
12.8656 |
1.0612 |
inf |
1.0996 |
| estimated fc by edgeR | 60.4244 | 24.121 | 58.9655 | 5.3961 | 1192.127 | 29.3642 | 1.0736 | 60.4244 | 1.1299 |