Table 1.

Median z-scores and average predicted folding free energy for influenza B (+)RNA, (−)RNA and synonymous codon mutant (mut (+)RNAs)

Segment		Z-score (+)RNA	Z-score Mut (+)RNA	Z-score (−)RNA	ΔG°37(+)RNA	ΔG°37Mut (+)RNA	ΔG°37(−)RNA
5	NP	−2.0	−0.7	−1.2	−494.5	−493.5	−485.7
8	NS	−1.6	−0.6	−1.0	−279.4	−283.1	−264.5
2	PB1	−1.6	−0.8	−1.8	−601.7	−624.1	−580.9
1	PB2	−1.3	−0.7	−1.2	−600.6	−638.2	−538.2
7	M1/BM2	−0.3	−0.2	1.1	−276.6	−290.8	−245.6
4	HA	0.0	−0.3	0.0	−485.1	−511.4	−506.7
3	PA	0.2	−0.1	−0.6	−552.0	−593.0	−501.3
6	NA	1.1	0.6	1.2	−384.2	−409.5	−374.8

Negative z-scores below −0.67 reveal GORS.