Table 2.
Multivariate Association of GLP-1 and relevant cardiovascular risk factors with total plaque burden as assessed by CT-angiography
|
Variables |
Total plaque |
|
|---|---|---|
| OR (CI) | p | |
| log GLP-1 |
2.53 (1.12 – 6.08) |
0.03 |
| Age |
1.15 (1.10 – 1.22) |
< 0.001 |
| Sex |
13.92 (4.47 – 51.53) |
< 0.001 |
| BMI |
1.20 (1.05 – 1.39) |
0.01 |
| Hypertension |
1.01 (0.38 – 2.65) |
0.98 |
| Diabetes |
2.11 (0.47 – 12.42) |
0.36 |
| Smoking |
6.04 (1.37 – 35.42) |
0.03 |
| LDL |
1.00 (0.99 – 1.01) |
0.80 |
| log CRP |
1.15 (0.45 – 3.18) |
0.78 |
| log TG |
2.22 (0.71 – 7.41) |
0.18 |
| log eGFR | 1.15 (0.08 – 18.37) | 0.92 |
Odds ratio and 95% CI increase in plaque quantity for 1 pM of total GLP-1 raise in plasma levels are presented.
Abbreviations:LDL (low density cholesterol), CRP (hsCRP), TG (triglyceride), eGFR (estimate glomerular filtration rate), log. Logarithmic.
Bold numbers indicate significant associations with p < 0.05.