Table 2.

IC50 values of commonly used anti-malarial drugs in in vitro culture of Plasmodium falciparum and in Plasmodium vivax from Manaus, Amazonas State, Brazil

	P. falciparum				P. vivax
		IC50 (nM)				IC50 (nM)
Drug 1	No. of isolates	Geometric mean	95% CI 2	Range	No of isolates	Geometric mean	95% CI 2	Range
Chloroquine	64	361.8	266–492	9–3373	132	24.1	20–29	5–729
Quinine1	63	128.5	93–175	12–2174	-	-	-	-
Mefloquine	66	14.2	10–20	2–723	78	18.1	14–23	2–337
Artesunate1	51	3.4	3–4	0.3–52	-	--	--	-

¹Performed only in P. falciparum cultures; ²CI, confidence interval.