Table 4.
Study of univariate and multivariate association of change in CCQ score from exacerbation to stable state
|
Variable |
Univariate |
Multivariate |
||||
|---|---|---|---|---|---|---|
| B | 95% CI | P | B | 95% CI | P | |
| Type of exacerbation (inpatient vs. outpatient RC) |
−1.44 |
−1.56 to −1.32 |
<0.001 |
|
|
|
| Gender (men vs. women RC) |
−1.27 |
−1.38 to −1.17 |
<0.001 |
|
|
|
| BMI |
−0.004 |
−0.008 to −0.0002 |
<0.001 |
|
|
|
| Smoking (current vs. former-smoker RC) |
1.33 |
1.57 to 1.09 |
<0.001 |
|
|
|
| Lives with smokers (yes vs. no RC) |
1.44 |
1.12 to 1.75 |
<0.001 |
−0.25 |
−0.44 to −0.06 |
0.010 |
| Exacerbations previous year |
−0.25 |
−0.28 to −0.22 |
<0.001 |
0.04 |
0.01 to 0.07 |
0.007 |
| FEV1 (%) |
−0.023 |
−0.043 to 0.003 |
<0.001 |
|
|
|
| CAT at inclusion |
−0.057 |
−0.06 to −0.05 |
<0.001 |
|
|
|
| CCQ at inclusion | 0.84 | 0.80 to 0.87 | <0.001 | −0.46 | −0.52 to −0.04 | <0.001 |
The CCQ score change has been studied as a continuous variable and the strength of the association occurs through the beta coefficients obtained by linear regression. BMI, exacerbations previous year FEV1 (%) and CAT and CCQ at inclusion were continuous variables.
B Beta coefficient, CI confidence interval, RC Reference category.