Table 3.

Change of HADS total score (t0: baseline; t1:1 month; t2: 6 months; t3: 12 months, t4: 24 months)

	t0-t1	t1-t2	t2-t3	t3-t4	p t0-t1*	p t1-t2*	p t2-t3*	p t3-t4*
median	−1	0	0	0	0.020	0.272	0.342	0.571
(Q1/Q3)	(−4/1)	(−2/2)	(−2/3)	(−2/2)
mean	−1.33	0.35	0.38	−0.4
(SD)	(5.53)	(4.53)	(4.09)	(4.57)

* Wilcoxon-test