1. Coenzyme metabolism
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B12 biosynthesis; Thiamin biosynthesis; Riboflavin biosynthesis; Queuosine biosynthesis; Folate biosynthesis; Molybdenum cofactor biosynthesis
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2. Coenzyme uptake
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B12 & precursor transporters; Thiamin & precursor transporters; Riboflavin transporters; Queuosine & precursor transporters; Folate transporters
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3. Amino acid metabolism
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Methionine biosynthesis; Methionine & SAM recycling; Cysteine biosynthesis; Lysine biosynthesis; Glycine metabolism; Serine metabolism; Ornithine degradation; Leucine biosynthesis; Histidine biosynthesis; Threonine biosynthesis; Tryptophan biosynthesis; Amino acid biosynthesis
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4. Amino acid uptake
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Methionine transporters; Lysine transporters; Glycine transporters; Histidine transporters; Amino acid transporters
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5. Secondary metabolism
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Aminosugar biosynthesis; Citric acid cycle; Urea and agmatine utilization
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6. Metal homeostasis
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Cobalt transporters; Molybdenum & tungsten transporters; Magnesium transporters; Potassium transporters
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7. Nucleobase metabolism
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Purine metabolism; Pyrimidine metabolism
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8. Nucleobase uptake
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Purine & precursor transporters; Pyrimidine transporters
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9. Protein synthesis
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Ribosome biogenesis; Amino acyl-tRNA synthetases
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10. Miscellaneous |
Isozymes of B12-dependent enzymes; Multidrug resistance transporter; Polysaccharide degradation; Other or unknown functional roles |