Figure 7.

Localization of GC1 in the retina of untreated 21-day-old 30Rk mouse. GC1 labeling is predominantly found in the inner segment where it co-localizes with the anti-KDEL ER marker. Weak GC1 labeling is also detected in the OSs and outer plexiform layers. Labeling of a retina from WT (Balb/c) mice is shown for comparison with intense GC1 labeling detectable only in the OS and KDEL labeling in the inner segment. Representative micrographs are shown from the analysis of two WT and two 30Rk mice.