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. 2013 Jun 10;22(19):3976–3986. doi: 10.1093/hmg/ddt251

Figure 2.

Figure 2.

Muscle wasting phenotypes characterized in systemic mito-PstI mice. (A) Treadmill performance of control and systemic mito-PstI mice at 6 months of age, measured by number of falls during a 5 min running test at 9 m/min (n = 7–12 per group). (B) Ambulatory movement of control and systemic mito-PstI male mice at 6 months of age, measured by activity cage counting beam-crossings during a 12 h period. (C) Bone mineral density measured by DEXA scan in 6-month old control and systemic mito-PstI mice (n = 7–12 per group). (D) DEXA scan quantification (grams) of lean mass, fat mass and total amount of tissue from 6-month-old control and systemic mito-PstI female mice (n = 7–12 per group). (E) Total body weight of female and male mice at 6 months of age (n = 8–12 per group). (F) Weight of gastrocnemius and quadriceps (grams) of control and systemic mito-PstI mice at 6 months of age (n = 4–10 per group). Values are presented as mean±SEM (*P< 0.05, **P< 0.01, ***P< 0.001).