Figure 4.

Perfusion curve analysis of neoangiogenesis. Eight week old mice (n=6) were left uninduced, or induced to express the stable transgene for 28 days, leading to robust neoangiogensis. A. Baseline (Uninduced) measurements and post-induction (28 days transgene induction) measurements of the “change in intensity” were compared, with approximately a seven-fold increase in fluorescence observed. B. On doxycycline (uninduced control) perfusion curve (n=6), and C. 28 days off dox (induced) perfusion curve (n=6). (**** denotes p<0.0001).