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. 2013 Feb 28;54(5):823–831. doi: 10.1093/jrr/rrt016

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© The Author 2013. Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Therapeutic Radiology and Oncology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 2. — (A) Gross skin changes in 15, 30, 50 and 75 Gy fields. Erythematous changes, wet desquamation and ulceration began to appear 4, 6 and 9 weeks after irradiation, respectively. (B–C) Histologic evaluation of full-thickness biopsy specimens after 30 Gy (H&E, magnification ×100 and ×400). (D) Gross skin changes according to RTOG grading of acute skin toxicity are plotted against time after irradiation.