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. 2013 Apr 14;54(5):852–862. doi: 10.1093/jrr/rrt029

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© The Author 2013. Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Therapeutic Radiology and Oncology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 7. — Histological section of Oreochromis niloticus spleens at 1 week post-radiation. (A) Control spleen with normal histology with the presence of melanin pigments (white arrowheads). (B) Irradiated spleen. Notice the absence of melanin pigments, the hyperplasia in the melanomacrophage cells (yellow circles highlight), and the increased amount of vacuolation (yellow arrows). (C) MRN-100 treated and irradiated spleen. Notice the presence of dark melanin cells (white arrowheads). (×40 magnification with H&E stain).