Table 1.
Characteristics of MESA Participants with Ascending Aortic Luminal Diameter Measurement (n= 3573) by Gender, 2000–02
| Women N=1940 Mean±SD or n (%) |
Men N=1633 Mean ±SD or n (%) |
p | |
|---|---|---|---|
| Cardiovascular Disease Risk Factors | |||
| Age, years | 60.6 ±10.0 | 60.5±10.0 | 0.73 |
| Race/ethnicity | 0.42 | ||
| Caucasian | 801 (41.3) | 700 (42.9) | |
| Chinese American | 214 (11.0) | 185 (11.3) | |
| African American | 601 (31.0) | 464 (28.4) | |
| Hispanic | 324 (16.7) | 284 (17.4) | |
| Body Surface Area (m2) | 1.76 ± 0.2 | 2.0 ±0.2 | <0.0001 |
| Total Cholesterol (mg/dl) | 199.54 ± 34.9 | 187.8±33.4 | <0.0001 |
| LDL Cholesterol (mg/dl) | 117.5±31.6 | 116.8± 29.7 | 0.44 |
| HDL Cholesterol (mg/dl) | 57.36±15.7 | 45.3±11.6 | <0.0001 |
| Triglycerides (mg/dl) | 123.3± 80.8 | 131.0±85.2 | 0.006 |
| Lipid Lowering Medication(Yes) | 315 (16.3) | 236 (14.5) | 0.14 |
| Hyperlipidemia | 862 (45.1) | 930 (57.7) | <0.0001 |
| Systolic BP (mmHg) | 125.1±22.8 | 124.5±18.8 | 0.34 |
| Diastolic BP (mmHg) | 69.35±10.3 | 75.1± 9.5 | <0.0001 |
| Mean BP (mmHg) | 88.0±13.2 | 91.5±11.5 | <0.0001 |
| Pulse Pressure (mmHg) | 55.8± 17.8 | 49.4± 14.3 | <0.0001 |
| Hypertension (Yes) | 838 (43.2) | 653 (40.0) | 0.053 |
| Hypertension Medication (Yes) | 715 (36.9) | 546 (33.4) | 0.030 |
| Diabetes (Yes) | 182 (9.4) | 187 (11.5) | 0.043 |
| Cigarette Smoking (Yes) | 791 (40.9) | 936 (57.5) | <0.0001 |
| Family History of Heart Attack (Yes) | 847 (46.1) | 595 (38.9) | <0.0001 |
| Measures of Subclinical Atherosclerosis | |||
| Coronary calcium score* | 0 (0–19.6) | 9.7 (0–130.9) | <0.0001 |
| Maximum CCA IMT (mm) | 0.8 (0.2) | 0.9 (0.2) | <0.0001 |
| Maximum ICA IMT (mm) | 1.0 (0.5) | 1.1 (0.6) | <0.0001 |
| Systemic Inflammatory Markers | |||
| IL-6 (pg/ml) | 1.5 (1.2) | 1.4 (1.2) | 0.004 |
| CRP (mg/l) | 4.5 (6.2) | 2.66 (5.3) | <0.0001 |
CCA IMT: common carotid artery intima media thickness, ICA IMT: Internal carotid artery intima media thickness.
*
Numbers given represents median (25th–75th percentile) for coronary calcium score