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Summary of binding parameters obtained from fluorescence studies.
| Protein | Ethanol | Butanol | Octanol | |||
|---|---|---|---|---|---|---|
| EC50 (mM) | nH | EC50 (mM) | nH | EC50 (mM) | nH | |
| WT | 51.7 ± 2.8 | 1.5 ± 0.1 | 25.8 ± 1.1 | 1.2 ± 0.06 | 0.7 ± 0.03 | 1.3± 0.07 |
| E582A | 113.7 ± 2.3 | 2.2 ± 0.1 | 59.9 ± 0.9 | 1.8 ± 0.06 | 2.6 ± 0.2 | 1.6 ± 0.31 |
| E582L | 148.7 ± 3.5 | 2.1 ±0.1 | 70.5 ± 1.8 | 1.4 ± 0.07 | 3.3 ± 0.06 | 2.2 ± 0.19 |
| E582H | 125.3 ± 3.6 | 2.2 ± 0.1 | 75.3 ± 1.9 | 2.2 ± 0.1 | 1.1 ± 0.07 | 1.9 ± 0.1 |
