Table 4.
Characteristics* | Univariate | Multivariate |
---|---|---|
| ||
Odds Ratio (95% CI), p-value | ||
Infant gestational age (weeks) | ||
Overall Effect | p<0.0001 | p<0.0001 |
34–37 vs. 38–40 | 1.89 (1.51–3,20), p<0.0001 | 2.20 (1.74–2.79), p<0.0001 |
34–37 vs. 41–42 | 2.44 (1.86–3.20), p<0.0001 | 3.14 (2.35–4.18), p<0.0001 |
38–40 vs. 41–42 | 1.29 (1.08–1.53), p=0.0049 | 1.42 (1.18–1.71), p=0.0002 |
Infant Race/Ethnicity* | ||
Overall Effect | p=0.0510 | p=0.1172 |
Caucasian compared to African American | 1.29 (1.10–1.51), p=0.0018 | 1.27 (1.07–1.50), p=0.0057 |
Hispanic compared to African American | 1.21 (0.98–1.49), p=0.0726 | 1.28 (1.03–1.60), p=0.0259 |
Infant birth weight (g) | ||
>3500 | 1.64 (1.46–1.83), p<0.0001 | 1.53 (1.36–1.73), p<0.0001 |
≤3500 | 1.00 | 1.00 |
Infant gender | ||
Male | 1.36 (1.22–1.51), p<0.0001 | 1.24 (1.11–1.40), p=0.0002 |
Female | 1.00 | 1.00 |
Maternal age (years) | ||
>20 | 1.27 (1.04–1.56), p=0.0217 | NS |
≤20 | 1.00 | |
Collection volume (ml) and delivery type | ||
≤80 | ||
Vaginal | NS | NS |
Caesarian | ||
>80 | ||
Vaginal | NS | 1.19 (1.04–1.37), p=0.0130 |
Caesarian | 1.00 | |
Processing time (hours) | ||
Overall Effect | p<0.0001 | p=0.0004 |
<10 hours vs. 10–23 hours | 1.16 (1.03–1.30), p=0.0139 | 1.12 (0.99–1.28), p=0.0687 |
<10 hours vs. ≥24 hours | 1.47 (1.23–1.76), p<0.0001 | 1.46 (1.21–1.76), p<0.0001 |
10–23 hours vs. ≥24 hours | 1.27 (1.07–1.51), p=0.0068 | 1.30 (1.08–1.56), p=0.0045 |
Viability (%) | ||
98–100 | NS | NS |
90–97 |
CI; Confidence Interval; NS: not significant;
Characteristics that were predictive of higher CD34+ content in either univariate or multivariate analysis were included. Viability of the cord blood cells was not associated with CD34+ content and was therefore not included in this table. All races/ethnicities were compared against each other in both univariate and multivariate analysis. Only the relationships that are statistically significant are shown in the table.