Table 5.
Clinical characteristics predictive of Post-TNCC >1.18×109 in univariate and multivariate analysis.
| Characteristics* | Univariate | Multivariate |
|---|---|---|
|
| ||
| Odds Ratio (95% CI), p-value | ||
| Infant gestational age (weeks) | ||
| Overall Effect | p<0.0001 | p<0.0001 |
| 34–37 vs. 38–40 | 0.63 (0.51–0.79), p<0.0001 | 0.62 (0.49–0.79), p=0.0001 |
| 34–37 vs. 41–42 | 0.49 (0.38–0.64), p<0.0001 | 0.51 (0.38–0.68), p<0.0001 |
| 38–40 vs. 41–42 | 0.78 (0.66–0.93), p=0.0060 | 0.82 (0.67–0.99), p=0.0409 |
| Infant race/ethnicity* | ||
| Overall Effect | p<0.0001 | p<0.0001 |
| Caucasian compared to African American | 1.44 (1.25–1.66), p<0.0001 | 1.54 (1.29–1.84), p<0.0001 |
| Caucasian compared to More than One Race | 1.24 (0.87–1.77), p=0.2288 | 1.27 (1.04–1.55), p=0.0193 |
| Caucasian compared to Hispanic | 1.22 (1.03–1.43), p=0.0213 | 1.14 (0.94–1.37), p=0.1752 |
| Asian compared to African American | 1.19 (0.92–1.56) p=0.1914 | 1.59 (1.05–2.40), p=0.0275 |
| Infant birth weight (g) | ||
| >3500 | 1.85 (1.65–2.07), p<0.0001 | 1.37 (1.21–1.56), p<0.0001 |
| ≤3500 | 1.00 | 1.00 |
| Maternal age (years) | ||
| >20 | 1.31 (1.00–1.71), p=0.0480 | NS |
| ≤20 | 1.00 | |
| Collection volume (ml)+ | ||
| ≤80 | ||
| Vaginal | 1.41 (1.05–1.90), p=0.0228 | 1.41 (1.05–1.91), p=0.0242 |
| Caesarian | 1.00 | 1.00 |
| >80 | ||
| Vaginal | 1.18 (1.03–1.35), p=0.0170 | 1.25 (1.08–1.44), p=0.0023 |
| Caesarian | 1.00 | 1.00 |
| Vaginal | ||
| ≤80 | 0.15 (0.13–0.18), p<0.0001 | 0.15 (0.12–0.17), p<0.0001 |
| >80 | 1.00 | 1.00 |
| Caesarian | ||
| ≤80 | 0.12 (0.09–0.16), p<0.0001 | 0.13 (0.10–0.17), p<0.0001 |
| >80 | 1.00 | 1.00 |
| Processing time (hours) | ||
| Overall Effect | p<0.0001 | p=0.0001 |
| <10 hours vs. 10–23 hours | 1.18 (1.05–1.32), p=0.0061 | 1.08 (0.94–1.23), p=0.2674 |
| <10 hours vs. ≥24 hours | 1.60 (1.34–1.91), p<0.0001 | 1.54 (1.26–1.88), p<0.0001 |
| 10–23 hours vs. ≥24 hours | 1.36 (1.14–1.61), p=0.0006 | 1.42 (1.18–1.73), p=0.0003 |
| Viability (%) | ||
| 98–100 | 1.09 (0.97–1.22), p=0.1649 | NS |
| 90–97 | 1.00 | |
CI: Confidence Interval; NS: Not significant;
*
Infant gender was not significantly associated with TNCC content and therefore was not included in this table.
*
All races/ethnicities were compared against each other in both univariate and multivariate analysis. Only the relationships that are statistically significant are shown in the table.