Figure 1.

A framework of network pharmacology study of Chinese medicine. The genes involved in anti-MI mechanism of XST were first detected with microarray gene expression analysis and rat genome database (RGD). The target information of the major ingredients was collected from literatures manually and validated experimentally in vitro. The compound-target-pathway network and compound-pathway network on anti-MI of XST were constructed to illustrate the multicompound, multitarget, multipathway, and multi-MOA regulatory mechanism of XST.