Table 2.
Liver protective effect on liver homogenate parameters of different experimental groups.
| Treatment | MDA (nmol/g protein)1 |
NO (µM/mg protein)1 |
SOD (U/mg protein)1 |
FRAP (mM FeII/mg protein)1 |
|---|---|---|---|---|
| Normal control (PBS) | 3.20 ± 0.22a | 10.13 ± 0.18a | 17.17 ± 0.74a | 9.42 ± 1.0 a |
| Ethanol control (50% ETOH + PBS) | 7.25 ± 0.08 | 15.09 ± 0.86 | 12.46 ± 2.51 | 5.28 ± 0.01 |
| Positive control (50% ETOH + silybin (50 mg/kg)) | 4.95 ± 0.08a | 10.20 ± 3.08a | 18.54 ± 0.37a | 15.02 ± 0.07a |
| 50% ETOH + SBE (200 mg/kg) | 3.02 ± 0.25a | 9.55 ± 0.35a | 19.38 ± 0.10a | 6.59 ± 0.03 |
| 50% ETOH + SBE (1000 mg/kg) | 2.93 ± 0.34a | 9.54 ± 0.04a | 20.08 ± 1.58a | 6.24 ± 0.04 |
| 50% ETOH + NESTE (200 mg/kg) | 2.22 ± 0.17a | 9.55 ± 0.58a | 19.44 ± 0.67a | 9.42 ± 0.02a |
| 50% ETOH + NESTE (1000 mg/kg) | 1.34 ± 0.23a | 8.45 ± 0.27a | 20.53 ± 0.24a | 12.78 ± 0.10a |
1Values are expressed as mean ± S.E.M (n = 8), avalues are significantly different from ethanol control (P < 0.05), MDA: malondialdehyde, NO: nitric oxide, SOD: superoxide dismutase, FRAP: ferric reducing antioxidant power.