Table 5.

Pharmacokinetic parameters of the CEG and selected SLN formulations.

Formulation code	C max⁡ (μg/mL)	T max⁡ (h)	AUC (μg · hr/mL)
Commercial gel*	1.01 ± 0.087	4	10.98 ± 0.039
GMNG-3	5.11 ± 1.07	6	92.8 ± 1.012
SANG-3	3.98 ± 1.42	6	68.74 ± 1.49
GLNG-3	8.21 ± 1.34	4	167.8 ± 1.24

*1 g gel formulation equivalent to 11.6 mg Diclofenac Diethylammonium for commercial gel (10 mg Diclofenac sodium).

^†100 mg gel formulation equivalent to 1 mg of Diclofenac sodium for GLNG-3,GMNG-3 and SANG-3.

All data expressed as mean ± S.D.; n = 6; (P ≤ 0.05).