Table 5.
Formulation code | C max (μg/mL) | T max (h) | AUC (μg · hr/mL) |
---|---|---|---|
Commercial gel* | 1.01 ± 0.087 | 4 | 10.98 ± 0.039 |
GMNG-3 | 5.11 ± 1.07 | 6 | 92.8 ± 1.012 |
SANG-3 | 3.98 ± 1.42 | 6 | 68.74 ± 1.49 |
GLNG-3 | 8.21 ± 1.34 | 4 | 167.8 ± 1.24 |
*1 g gel formulation equivalent to 11.6 mg Diclofenac Diethylammonium for commercial gel (10 mg Diclofenac sodium).
†100 mg gel formulation equivalent to 1 mg of Diclofenac sodium for GLNG-3,GMNG-3 and SANG-3.
All data expressed as mean ± S.D.; n = 6; (P ≤ 0.05).