Table 1.
Study | No. of donors | Age range | Culture condition | Proliferation | Osteo-genesis | Adipo-genesis | Chondro-genesis | Origin of ASC |
---|---|---|---|---|---|---|---|---|
Van Harmelen et al. 2004 [22] |
29 |
17-61 |
DMEM/F12 + 10%FCS |
↓ |
|
↓ |
|
Abdominal subcutaneous fat and omental fat |
de Girolamo et al. 2009 [24] |
26 |
21-68 |
DMEM + 10%FBS |
|
↓ |
↓ |
|
Abdominal subcutaneous fat |
Zhu et al. 2009 [23] |
26 |
20-58 |
DMEM + 10%FBS |
→ |
↑ |
→ |
|
Abdominal subcutaneous fat |
Alt et al. 2012 [3] |
40 |
15-71 |
α-MEM + 20% FBS |
↓ |
↓ |
↓ |
↓ |
Abdominal subcutaneous fat |
Chen et al. 2012 [20] |
22 |
36-71 |
KFSM + NAC + 5% FBS |
→ |
→ |
|
|
Gluteal fat |
Present study | 27 | 30-60 | KFSM + NAC + 5% FBS | → | → | ↓ | → | Abdominal subcutaneous fat |
NAC N-acetyl cysteine.
KFSM keratinocyte serum free medium.
FBS fetal bovine serum.
FCS fetal calf serum.