. Author manuscript; available in PMC: 2013 Sep 8.

Published in final edited form as: Sci Transl Med. 2012 Jul 11;4(142):142ra94. doi: 10.1126/scitranslmed.3003989

Table 1.

Intersection of the candidate cancer driver mutations (CDMs) and their interaction partners in the Reactome Functional Interaction Network with the cancer-associated proteins (CAPs). It is assumed that a CDM can be monitored by measuring the protein encoded by the CDM or in the sub-network of CDMs.

Cancer associated proteins (CAPs)		Overlap of CDMs with CAPs	# of CAPs in the sub-network of CDMs	p-value (Enrichment of CAPs in the sub-network of CDMs)	# of CDMs that can be monitored by CAPs (out of 379)
All	1172	43	608	4.3e⁻¹¹	175
Detectable (plasma and urine combined)	473	18	232	5.9e⁻⁵	143